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Hyaluronic Acid(HA) is… Hyaluronic acid(HA) is a naturally occurring polymer found in all living organisms.1 The human dermis has a high percentage of HA, which hydrates the skin because of its high water-binding properties. HA is the predominant part of the viscoelastic intracellular matrix, which provides and maintains proper tissue volume and acts as a cushion to help protect the skin.1
The natural product, if injected into the skin, would be rapidly lost. To produce a longer-lasting HA, it must be made more robust and stable by cross-linking.* Cross-linked gels combine with naturally occurring HA to provide volume and support for 4 to 12 months.2 - 3

1. Born T. Hyaluronic acids. Clin Plast Surg 2006; 33:525-38.
2. Carruthers A, Carruthers J. Non-animal based hyaluronic acid fillers: scientific and technical    considerations. Plast Reconstr Surg 2007;120:33S.
3. Tmothy C Flynn. Comparative Histology of Intradermal Implantation of Mono and Biphasic    Hyaluronic Acid Fillers. Dermatol Surg 2011;37:1-7.

New Hyaluronic Acid Dermal Filler, Neuramis® Neuramis® is the NEW hyaluronic acid dermal filler for deep and fixed wrinkles, volume and rejuvenation of the skin. Neuramis® products are manufactured using Medytox’s unique double’ cross-linking technology, SHAPE technology, to be made stable gels. It minimizes uncross-linked BDDE and guarantees 3 values.

SHAPE Technology of Neuramis® Neuramis®, the ideal HA dermal filler, is manufactured using SHAPE technology which Medytox has developed.
- SHAPE(Stabilized Hyaluronic Acid & Purification Enhancement)

3 values of Neuramis®

* Cross-linking is a chemical process of bonding one polymer chain to another to create a larger, more stable molecule.

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Which area do your patients most want to be treated with Neuronox?
a. Glabellar lines
b. Crow’s feet
c. Forehead lines
d. Masseter
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